| Wesley Snipes | Blade/Eric Brooks/The Daywalker |
| Kris Kristofferson | Abraham Whistler |
| Stephen Dorff | Deacon Frost |
| Donal Logue | Quinn |
| N'Bushe Wright | Dr. Karen Jenson |
| Udo Kier | Vampire Elder Dragonetti |
| Arly Jover | Mercury |
| Traci Lords | Racquel |
| Devon Sawa | Vanessa |
| Kevin Patrick Walls | Officer Krieger |
| Director | Stephen Norrington; David S. Goyer |
| Producer | Wesley Snipes; Peter Frankfurt; Robert Engelman; Stan Lee |
| Writer | David S. Goyer; Marv Wolfman |
| Cinematography | Theo van de Sande |
| Musician | Mark Isham; DJ Krush |
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| Interactive Animated Menus Original Theatrical Trailer Isolated Score with Commentary by Composer Audio Commentary including: - Wesley Snipes - Stephen Dorff - David S. Goyer - Theo Van De Sande - Kirk M. Petruccelli - Peter Frankfurt Featurettes: - La Magra - Designing Blade - The Origins of Blade - The Blood Tide Pencil to Post House of Erebus Cast and Crew Bios and Filmographies Enhanced Features for your PC: - Original Screenplay - Access to the Script - Balde Highlights - Web links and more |